Therapeutic Biologics Research

Exponential power to engineer novel therapeutics

From early discovery through development, MindWalk integrates Bio-Native AI, deep data, and advanced lab research into a customizable ecosystem engineered to support precision, deepen diversity, and enable confident discovery.

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Workflows built for complex discovery

Contributed to advancing 15+ clinical candidates

Precision biologic insight driven by AI, data, and advanced lab research—designed to bring blind spots into view and support complex discovery programs.

Continuity, seamless handoffs
One workflow bridging target analysis to IND-enabling readiness

Stronger starts
Risk considerations brought forward early to help avoid costly late-stage surprises

360° intelligence with transparent insight
Powered by LensAI™, integrated biological and functional data provide a transparent, explainable view of each candidate’s strengths and areas of uncertainty

A customizable ecosystem

No two programs are alike. Our approach adapts to your challenges with diversity-driven workflows designed to surface rare candidates with strong translational potential and support more targeted experimental design.

One system + Connected intelligence + Transformative insight 

Therapeutics - Speed Diversity Confidence Graphic

Speed

  • Stronger starts
  • Reduced time to lead selection

Integrated workflows help flag areas of potential risk earlier

Diversity

  • Rare, high-value candidates brought into focus
  • Deep insight across phenotypic diversity highlights patterns not visible in isolated data

Broad, connected datasets add depth—revealing opportunities across discovery programs

Confidence

  • Evidence-based discovery
  • Contributed to programs supporting 15+ clinical candidates
  • >98% B cell Select™ success rate*

Deep biological data and predictive modeling bring risk considerations forward

*“Success” refers to meeting predefined discovery criteria, not clinical or therapeutic outcomes. Results may vary.

Therapeutics - Speed Diversity Confidence Graphic

Speed

  • Stronger starts
  • Reduced time to lead selection

Integrated workflows help flag areas of potential risk earlier

Diversity

  • Rare, high-value candidates brought into focus
  • Deep insight across phenotypic diversity highlights patterns not visible in isolated data

Broad, connected datasets add depth—revealing opportunities across discovery programs

Confidence

  • Evidence-based discovery
  • Contributed to programs supporting 15+ clinical candidates
  • >98% B cell Select™ success rate*

Deep biological data and predictive modeling bring risk considerations forward

*“Success” refers to meeting predefined discovery criteria, not clinical or therapeutic outcomes. Results may vary.

Revealing what was once unseen

Every discovery holds hidden biologic patterns that reveal what to pursue, refine, or reimagine. MindWalk integrates intelligent analysis with experimental depth to interpret those patterns—an approach designed to support the development of differentiated therapeutic candidates.

Your success is our success

Collaboration drives every project. We listen, adapt, and align with your goals, applying scientific and technological rigor with advanced workflows to deliver reliable insights and support progress. For us, success is measured by the progress of your discoveries.

“LensAI solves a foundational problem—making biological data interoperable and accessible at scale. It brings context into view, giving us the kind of resolution you’d expect from modern data systems—and that changes everything.” - Jeff Fried, Advisory Board Member, MindWalk

Where our research makes a broad impact

Oncology  +  Infectious Disease  +  Neurodegeneration  +  Metabolic Disease  +  Rare Disease  +  Inflammation  +  Market Kits

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Biologics discovery across complex targets

Contributed to 15+ molecules advancing to the clinic

Antibody discovery + development

LensAI Bio-Native Suite:

  • HYFT Base™ Data Integration and Insights: Target Profiling, Off-target & Cross-reactivity, Antigen Design, Epitope Prediction, Epitope Specificity Analysis, Protein Structure Prediction, GMX (MD Applications)
  • HYFT Matrix™ Exploration Layer: Epitope Mapping, Affinity Predictions (MD), Hit Selection, Developability Assessment, Immunogenicity Screening, Hit Expansion
  • HYFT Prime™ Engineering and Design Engine: Humanization, De-risk Engineering, Binding Affinity Optimization, Target Specificity and Selectivity

Integrated Therapeutic Discovery AI/Data/Lab:

Target

  • Target Analysis
  • Tool Generation
  • HYFT Base

Discovery

  • Immunization Strategies
  • B cell Select®, Hybridoma and Yeast Display Discovery
  • De novo Design
  • HYFT Matrix & HYFT Prime

Leads

  • Lead Characterization
  • Lead Optimization
  • Protein Engineering and Production
  • HYFT Matrix & HYFT Prime

Candidate Selection

  • Research Cell Bank Generation

Functional selection

  • Internalization
  • Neutralization
  • Epitope Mapping
  • Affinity, Specificity, Developability
  • Custom Cell-based and Plate-based Assays

Species Diversity

Rabbit + Chicken + Camelid + Mice

Immunization Strategies

Protein + Genetic + Peptide + Whole Cell

Format Options

  • Full-length IgG
  • Bispecific Antibodies (bsAbs)
  • VHH / Nanobody
  • scFv, Fab, F(ab’)2
  • Custom Formats
  • Fusion Constructs

Expanding discovery innovation

Vaccines + Peptide Therapies + Cell Therapies + Other Biologics

Let’s shape the future

One biointelligent ecosystem,
explore partnership opportunities 

Change tomorrow

Used by teams across 19 of the top 20 pharma companies, next-gen biotechs, and top research institutions.

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Let’s expand what’s possible for human health

Case Studies

See validated insights that redefine workflows and advance discovery

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Scientific Posters

Discover how MindWalk powers smarter paths from concept to clinic.

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Blogs

Explore latest ideas reshaping the future of discovery.

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Four ways to access MindWalk

We build it

Customizable offerings in biologics discovery—from target analysis to optimized leads.

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You build it

Access to state-of-the-art LensAI SaaS Platform.

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The Vault

Smarter starts: a portfolio of partner-ready assets.

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Partnership

We are proud to partner with the best in pharma, biotech and academia organizations. Join us in creating future of human health.

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