Expand what you can discover
Rabbit B cell antibody discovery with B cell Select®
MindWalk is a leader in rabbit B cell antibody discovery, with decades of specialized experience behind our proprietary B cell Select® platform. We combine the breadth of the rabbit immune repertoire with function-first screening and native heavy/light-chain recovery. LensAI™ analysis extends discovery with deeper insight into candidate function, specificity, and potential.
Delivering customized antibody discovery across therapeutic, anti-idiotypic, anti-drug, diagnostic, and research applications.
300+
B cell Select® programs completed
>98% antibody discovery success*
*Success refers to meeting predefined discovery criteria, not clinical or therapeutic outcomes. Results may vary.
35+ years
antibody discovery expertise
Find functional candidates early.
B cell Select® is designed to bring functional relevance into rabbit antibody discovery early, helping teams move beyond binding alone and focus on the candidates best aligned with program goals.
The advantage is in the combination:
+ Deep access to diverse, in vivo-matured immune responses
+ Antigen-specific memory B cell enrichment to recover relevant candidates
+ Function-first screening early in discovery
+ Native heavy/light chain pair recovery
+ A broader, functionally resolved candidate landscape
*B cell discovery available in additional species.
Proprietary B cell Select® is designed to capture biological diversity at the onset and translate it into relevant, functional candidates.
LensAI™ analysis on every hit.
B cell Select® candidates are evaluated with LensAI™ for function, developability, immunogenicity, and epitope characteristics before advancement decisions.
See more before you advance
Rabbit expands the search space, with the flexibility to integrate data and AI for deeper candidate insight and build on each discovery to reveal more of what the repertoire can offer. Work 1:1 with a dedicated team of experts focused on your campaign goals.
LensAI™ analysis
Fit-for-purpose applications evaluate candidate function, developability, immunogenicity, epitope characteristics, and other advancement considerations.
Rabbit antibody discovery across applications
The discovery strategy can be customized around program goals.
Therapeutic antibodies
Rabbit antibody discovery for difficult targets, differentiated epitopes, functional selection, humanization, and optimization.
Research
Antibodies developed around target and application-specific performance requirements such as IHC/ICC or flow cytometry reagents
Rabbit-derived antibodies in preclinical and clinical development
OncoResponse highlight
MindWalk’s B cell Select® platform contributed to the discovery of OR502 and OR641, two rabbit-derived oncology programs advanced by OncoResponse.
OR502
Humanized rabbit-derived anti-LILRB2 antibody in active Phase 1/2 clinical development for advanced solid tumors.
OR641
Humanized rabbit-derived dual LILRB1/LILRB2 antagonist in preclinical/IND-enabling development.
These programs illustrate a path from rabbit B-cell discovery into downstream therapeutic development. Additional client programs have advanced but are not publicly disclosed. MindWalk’s contribution was at the discovery stage. OncoResponse owns and develops the programs.
Explore published research and publicly disclosed programs →
Tell us about your target.
A scientist, not a sales rep, replies within two business days.
FAQs
-
What is B cell Select®?
B cell Select® is MindWalk’s proprietary rabbit B cell antibody discovery platform, combining antigen-specific B cell enrichment, early primary B cell screening, native heavy/light-chain recovery, and custom functional characterization options tailored to your unique target and biology.
-
What is function-first antibody discovery?
Function-first antibody discovery introduces relevant biological or application-specific activity early enough to influence which antibodies move forward rather than prioritizing candidates on binding alone.
-
What are the unique advantages to using a rabbit host for antibody discovery?
Rabbit immune biology generates exceptional repertoire diversity, high affinity binders, and differentiated epitope recognition opportunities through a combination of unique somatic V gene conversion, hypermutation, and expanded CDR3 loop lengths, creating discovery opportunities across conserved, conformationally constrained, cryptic, and other challenging target types.
-
Can rabbit antibodies be humanized?
Yes. Rabbit-derived antibodies can be humanized and further engineered for human therapeutic development.