LensAI™ Powered by HYFT® Technology

AI analysis for antibody discovery, inside every MindWalk program.

Our scientists use LensAI™ to compare candidates across the evidence that matters: biological context, structure, function, assay data, developability, immunogenicity, and diversity. Every prediction is confirmed at the bench before it shapes a decision.

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See more of what matters, earlier.

LensAI expands how deeply biology can be explored. Moving beyond static datasets, it reveals cross-modal patterns that surface meaningful, non-obvious biological relationships. By bringing multiple complex data types into a single analytical framework, it supports more confident and efficient discovery workflows. Powered by HYFT® technology, it links every candidate to conserved biological patterns.

 

How LensAI™ works inside a program.

LensAI™ connects sequence, structure, function, and literature into one traceable view of each candidate. It is delivered inside MindWalk discovery programs, with our scientists interpreting every result.

Integration at the core

Unifying sequence, structure, function, and literature into connected biological context. With 25B+ mapped relationships, they provide traceable links between data and evidence—enabling explainable insights.  

Context from the start

Every input—from a single sequence to multi-omics datasets—is mapped to structural, functional, and literature context. Fragmented data becomes searchable, explainable knowledge that supports discovery from the first step.

Earlier decisions

This foundation supports in silico screening, risk assessment, and functional prediction in early discovery—helping teams evaluate and prioritize candidates within a connected biological context.

HYFT® technology: the patterns evolution kept.

HYFTs are characteristic biological subsequences retained through evolution because they carry the minimum information needed to predict a molecule’s structure and function. That is what the model reasons over: conservation, the evidence of function a biologist already trusts.

LensAI Overview HYFT module

01 HYFT

Analyze massive data sets—at once

Screen extensive collections of sequences, compounds, or biologics in parallel using discovery-scale analysis and sub-sequence granularity for deep biological clarity.

02 HYFT

Surface non-obvious patterns and biological context

Reveal functional and structural relationships across vast datasets—uncovering mechanisms, liabilities, and opportunities invisible to traditional analysis alone.

03 HYFT

Start with as little as a sequence

From minimal input, HYFTs infer structure, function, and activity—delivering biological context and mechanistic understanding instantly.

04 HYFT

Traceable data that strengthens precision

Every datapoint is connected to its biological evidence, delivering transparent, reproducible insights suitable for scientific and regulatory review.

The power of HYFTs

01 HYFT

Analyze massive data sets—at once

Screen extensive collections of sequences, compounds, or biologics in parallel using discovery-scale analysis and sub-sequence granularity for deep biological clarity.

02 HYFT

Surface non-obvious patterns and biological context

Reveal functional and structural relationships across vast datasets—uncovering mechanisms, liabilities, and opportunities invisible to traditional analysis alone.

03 HYFT

Start with as little as a sequence

From minimal input, HYFTs infer structure, function, and activity—delivering biological context and mechanistic understanding instantly.

04 HYFT

Traceable data that strengthens precision

Every datapoint is connected to its biological evidence, delivering transparent, reproducible insights suitable for scientific and regulatory review.

LensAI™ modules

One analytical environment, three stages.

Target. Candidates. Lead.

Talk to a scientist

x

LensAI™

Data + Insights Foundation

HYFT base
  • Full data integration for single-query access across sequence, structure, and function
  • Explore using the power of billions of pre-indexed HYFT patterns to uncover biological connections between targets, mechanisms, and therapeutic relevance
  • Start with our framework—or add your data—to instantly access deep biological context, with or without custom inputs
  • Continuously enrich and adapt insights as data evolves
Application

Data Management

Target Profiling

Off-target & Cross-reactivity Screening

Antigen Design

Epitope Prediction

Epitope Specificity Analysis

Protein Structure Prediction

GMX (MD applications)

x

LensAI™

Exploration Layer

HYFT matrix
  • Uncover hidden candidates that share critical patterns with top performers
  • Prioritize true diversity by scoring across mechanisms, epitopes, formats, and biological context
  • Filter faster with biological intelligence to reduce downstream experimentation and refine focus
  • Advance with confidence through transparent scoring that shows what matters and why
Application

Epitope Mapping

Paratyping

Developability Assessment

Affinity Prediction

Hit Expansion

Immunogenicity Screening

x

LensAI™

Engineering & Design Engine

HYFT prime purple
  • Multi-dimensional optimization — immunogenicity, affinity, and developability in one integrated loop
  • Refine and select using multi-dimensional biological evidence, not isolated properties
  • Advance molecules engineered for performance, scalability, and clinical translation
  • Generate de novo candidates through LensAI reasoning over HYFT molecular fingerprints
Application

Epitope Mapping

Developability 

Humanization

Binding Affinity

Immunogenicity

pH Selectivity

LensAI™

Data + Insights Foundation

HYFT base
Link arrow bottom right
x

LensAI™

Data + Insights Foundation

HYFT base
  • Full data integration for single-query access across sequence, structure, and function
  • Explore using the power of billions of pre-indexed HYFT patterns to uncover biological connections between targets, mechanisms, and therapeutic relevance
  • Start with our framework—or add your data—to instantly access deep biological context, with or without custom inputs
  • Continuously enrich and adapt insights as data evolves
Application

Data Management

Target Profiling

Off-target & Cross-reactivity Screening

Antigen Design

Epitope Prediction

Epitope Specificity Analysis

Protein Structure Prediction

GMX (MD applications)

LensAI™

Exploration Layer

HYFT matrix
Link arrow bottom right
x

LensAI™

Exploration Layer

HYFT matrix
  • Uncover hidden candidates that share critical patterns with top performers
  • Prioritize true diversity by scoring across mechanisms, epitopes, formats, and biological context
  • Filter faster with biological intelligence to reduce downstream experimentation and refine focus
  • Advance with confidence through transparent scoring that shows what matters and why
Application

Epitope Mapping

Paratyping

Developability Assessment

Affinity Prediction

Hit Expansion

Immunogenicity Screening

LensAI™

Engineering & Design Engine

HYFT prime
Link arrow bottom right
x

LensAI™

Engineering & Design Engine

HYFT prime purple
  • Multi-dimensional optimization — immunogenicity, affinity, and developability in one integrated loop
  • Refine and select using multi-dimensional biological evidence, not isolated properties
  • Advance molecules engineered for performance, scalability, and clinical translation
  • Generate de novo candidates through LensAI reasoning over HYFT molecular fingerprints
Application

Epitope Mapping

Developability 

Humanization

Binding Affinity

Immunogenicity

pH Selectivity

From sequence to full biological context—at scale

Start with a single sequence and scale across the service-based discovery continuum. LensAI connects data to structural and functional evidence to deliver a traceable, 360° biological view that supports decision-making across workflows.

New FDA guidance: AI derived data now accepted in IND filings

In January 2025, the FDA clarified that AI-based findings can be part of IND submissions when they’re transparent, reproducible, and traceable. HYFTs® structure and connect complex data to meet those standards—turning AI insight into evidence ready for regulatory review.

“LensAI solves a foundational problem—making biological data interoperable and accessible at scale. It brings context into view, giving us the kind of resolution you’d expect from modern data systems—and that changes everything.”

 - Jeff Fried, Advisory Board Member, MindWalk

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Explore key workflows and underlying functionality

Case Studies

See validated insights that redefine workflows and advance discovery.

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Scientific Posters

Discover how MindWalk powers smarter paths from concept to clinic.

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Blogs

Explore latest ideas reshaping the future of discovery.

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Transform your pipeline

Partner-ready assets ready for advanced start or co-creation.

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Tech partners

We collaborate with technology leaders to extend the power of LensAI™, combining advanced computing and data platforms with HYFT® technology to help accelerate discovery.

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Four ways to access MindWalk

We build it

Customizable offerings in biologics discovery—from target analysis to optimized leads.

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You build it

Access to state-of-the-art LensAI SaaS Platform.

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The Vault

Smarter starts: a portfolio of partner-ready assets.

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Partnership

We are proud to partner with the best in pharma, biotech and academia organizations. Join us in creating future of human health.

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