LensAI™ Multi-omics Data

A critical key to making AI useful in drug discovery

Biologics discovery produces billions of raw files—but data alone isn’t insight. HYFT® technology transforms sequences, structures, assay outputs, and omics at ingestion, providing contextual access that makes AI and deep data explainable and scalable across discovery.

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The market challenge: disconnected data is the core barrier to scaling AI in discovery

Moving from siloed data to a connected system

Disconnected sources increase time to decision

Inconsistent formats limit comparability

Predictions lack biological grounding

LensAI powered by HYFT technology

Transforming big data to deep data

Patented HYFTs are the foundation of our bio-native intelligence—transforming input, from a single sequence to large-scale datasets, into connected biological context. Available through our expert-led service projects, HYFTs give you access to a knowledge base of 25B+ biologic relationships, where each datapoint is linked to underlying context, evidence, and provenance. More than raw data, it’s a dynamic network that grows as new data is integrated.

From hidden patterns to clear biologics insight

With biologically fluent intelligence, HYFTs surface relationships that often remain overlooked, helping researchers identify critical insights within their discovery workflows.

Simultaneously explore your siloed data

HYFTs make your data AI-ready by design—engineered for scale, transparency, and traceability. A single query connects data across sources instantly, delivering explainable, real-time results enriched with traceable source information, versioning, and biological context. A reproducible data layer that helps build clarity and confidence in AI-powered discovery.

Deep data:
Each datapoint has instant context.
Each new dataset enriches the graph.

Data Integration - Data Key-1
Data Integration - Data image

Biologics integration across multiple modalities

HYFTs connect sequences, structures, functions, assay outputs, and literature into one biologically fluent layer—delivering depth, context, and evidence with every query.

Sequences

More than a string—indexed against motifs, structures, physicochemical properties, and literature.
(Genomics, transcriptomics, proteomics, metabolomics)

Structural Biology

More than coordinates—it’s tied to binding surfaces, epitopes, and assay outputs to explain function.

Assay Outputs

More than a curve—it’s linked to the clone and (sub) sequence for reproducibility.
(Immunization, discovery platforms, characterization, optimization, patient lab work, etc)

Literature, IP, and Various Databases

More than text—mapped to (sub) sequences, structures, and assay outputs so published knowledge directly informs discovery.
(Unstructured data: scientific journals, patient records, patent information—structured data: chemical, omics)

Deep data transforms biologics discovery

Pharma success is measured in speed, confidence, and evidence. HYFTs move the needle on all three.

  • Earlier biological context across discovery workflows
  • Traceable, evidence-linked data to support risk-aware decisions
  • Biologically fluent data to inform design and optimization
  • Built for compounding knowledge reuse across programs

New FDA guidance: AI derived data now accepted in IND filings

In January 2025, the FDA clarified its expectations for AI-derived information in drug and biologics submissions, emphasizing the need for transparency, reproducibility, and traceability of AI outputs within a defined context of use. HYFTs structure and connect complex biological data to support those criteria, helping turn explainable AI insight into evidence documented for regulatory review.

Exponential power connecting data, context, and discovery.

LensAI and HYFTs form a missing layer—transforming fragmented biologics data into connected, contextualized intelligence.

Data Integration - Exponential Power..

LensAI Platform
Predictive intelligence, generative design, and in silico reasoning that connect data to biology—bringing context and precision to discovery.

HYFT Bio-Native™ Intelligence
A foundation of 25B+ biologic intelligence objects that embed context and evidence into every datapoint—delivering explainable, scalable insight across discovery workflows.

Your Data/Models
Sequences, structures, assay outputs, omics, and literature from your programs come together seamlessly—transforming raw files into biologically fluent intelligence.

LensAI Bio-Native Suite

Transform your workflow—intelligence to adapt at every stage 

Foundation. Exploration. Engineering.

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HYFT Base™

Data and Insights Foundation

HYFT base
  • Full data integration for single-query access across sequence, structure, and function
  • Explore using the power of billions of pre-indexed HYFT patterns to uncover biological connections between targets, mechanisms, and therapeutic relevance
  • Start with our framework—or add your data—to instantly access deep biological context, with or without custom inputs
  • Continuously enrich and adapt insights as data evolves
Application

Data Management

Target Profiling

Off-target & Cross-reactivity Screening

Antigen Design

Epitope Prediction

Epitope Specificity Analysis

Protein Structure Prediction

GMX (MD applications)

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HYFT Matrix™

Exploration Layer

HYFT matrix
  • Uncover hidden candidates that share critical patterns with top performers
  • Prioritize true diversity by scoring across mechanisms, epitopes, formats, and biological context
  • Filter faster with biological intelligence to reduce downstream experimentation and refine focus
  • Advance with confidence through transparent scoring that shows what matters and why
Application

Affinity Prediction

Developability Assessment

Epitope Mapping

Hit Expansion

Hit Selection

Immunogenicity Screening

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HYFT Prime™

Engineering and Design Engine

HYFT prime purple
  • Multi-dimensional optimization — immunogenicity, affinity, and developability in one integrated loop
  • Refine and select using multi-dimensional biological evidence, not isolated properties
  • Advance molecules engineered for performance, scalability, and clinical translation
  • Generate de novo candidates through LensAI reasoning over HYFT molecular fingerprints
Application

Epitope Mapping

Developability

Humanization

Binding Affinity

Immunogenicity

pH Selectivity

HYFT Base™

Data and Insights Foundation

HYFT base
Link arrow bottom right
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HYFT Base™

Data and Insights Foundation

HYFT base
  • Full data integration for single-query access across sequence, structure, and function
  • Explore using the power of billions of pre-indexed HYFT patterns to uncover biological connections between targets, mechanisms, and therapeutic relevance
  • Start with our framework—or add your data—to instantly access deep biological context, with or without custom inputs
  • Continuously enrich and adapt insights as data evolves
Application

Data Management

Target Profiling

Off-target & Cross-reactivity Screening

Antigen Design

Epitope Prediction

Epitope Specificity Analysis

Protein Structure Prediction

GMX (MD applications)

HYFT Matrix™

Exploration Layer

HYFT matrix
Link arrow bottom right
x

HYFT Matrix™

Exploration Layer

HYFT matrix
  • Uncover hidden candidates that share critical patterns with top performers
  • Prioritize true diversity by scoring across mechanisms, epitopes, formats, and biological context
  • Filter faster with biological intelligence to reduce downstream experimentation and refine focus
  • Advance with confidence through transparent scoring that shows what matters and why
Application

Affinity Prediction

Developability Assessment

Epitope Mapping

Hit Expansion

Hit Selection

Immunogenicity Screening

HYFT Prime™

Engineering and Design Engine

HYFT prime
Link arrow bottom right
x

HYFT Prime™

Engineering and Design Engine

HYFT prime purple
  • Multi-dimensional optimization — immunogenicity, affinity, and developability in one integrated loop
  • Refine and select using multi-dimensional biological evidence, not isolated properties
  • Advance molecules engineered for performance, scalability, and clinical translation
  • Generate de novo candidates through LensAI reasoning over HYFT molecular fingerprints
Application

Epitope Mapping

Developability

Humanization

Binding Affinity

Immunogenicity

pH Selectivity

“LensAI solves a foundational problem—making biological data interoperable and accessible at scale. It brings context into view, giving us the kind of resolution you’d expect from modern data systems—and that changes everything.”

 - Jeff Fried, Advisory Board Member, MindWalk

See it in action

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Case Studies

See validated insights that redefine workflows and advance discovery

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Scientific Posters

Discover how MindWalk powers smarter paths from concept to clinic.

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Blogs

Explore latest ideas reshaping the future of discovery.

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Transform your pipeline

Partner-ready assets ready for advanced start or co-creation.

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Tech partners

We collaborate with technology leaders to extend the power of LensAI, combining advanced computing and data platforms with our bio-native intelligence to help accelerate discovery.

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Four ways to access MindWalk

We build it

Customizable offerings in biologics discovery—from target analysis to optimized leads.

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You build it

Access to state-of-the-art LensAI SaaS Platform.

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The Vault

Smarter starts: a portfolio of partner-ready assets.

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Partnership

We are proud to partner with the best in pharma, biotech and academia organizations. Join us in creating future of human health.

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